Page 77 - FoodFocusThailand No.200 November 2022
P. 77

STRATEGIC R&D

                       Relieve Unmanageable Pain: The     Precaution of CBD
                    key to effectively using CBD oil is finding   People must reference the suggested single-serving dosage when taking any of
                    the  optimal  dosage  for  pain  relief.   the various CBD products available. Advice for healthy adults: At high doses (300
                    According to a University of California,   mg), CBD might induce some side effects, including inhibition of hepatic drug
                    San Diego study, modest doses offer   metabolism, alterations of in vitro cell viability, and decreased fertilization
                    tolerable pain relief.  Data indicates that   capacity. 11, 15  As a precaution, the recommended doses is under 70 mg per day
                                    2
                    the  combination  of  CBD  and  other   (about 28 drops of 5% CBD) unless under medical direction. Advice for vulnerable
                    cannabinoids, particularly THC appears   groups: Pregnant and breastfeeding women or individuals taking medications,
                    particularly  effective  for  acute  pain   are not recommended CBD unless under medical direction.
                    conditions, including those associated
                    with multiple sclerosis and cancer. This
                    combination can reduce the dosage of                    More Information        Service Info C012
                    opioid medicines required to treat severe
                        3
                    pain,  reduce tolerance buildup to opioid
                    medicines,  and reduce the severity of
                             4
                    withdrawal symptoms.
                       Protect Against  Neurological
                    Disease: Studies show that CBD has
                    antioxidant   and  anti-inflammatory
                              5
                             6
                    properties. To aid in pain regulation and
                    provide a measure of neuroprotection,
                    an additional 2.5 mg of CBD and THC
                    dose (2.5 mg – 7.5 mg) may be taken. 2
                    These  benefits  are  particularly
                    advantageous for individuals suffering
                    from  Parkinson’s  or  Alzheimer’s
                    disease. 7
                       Ease Diabetic Complications: High
                    glucose  levels  typically  precede  the
                    development  of  diabetes  and  other
                    health  concerns;  however,  tests  on
                    human cells found that CBD decreases
                    glucose  levels  and  can  lessen  the
                    likelihood  of  future  health  issues. 8
                    Moreover, it can reduce the low-density
                    lipoprotein  (bad  cholesterol)  by
                    converting  them  into  high-density
                    lipoprotein  (good  cholesterol).   High
                                              9
                    levels of HDL cholesterol could lower the
                    risk for heart disease and stroke.

                    Safety of CBD
                    Various reports demonstrate that CBD
                    does not alter metabolic or physiological
                    parameters,  such  as  cell  and
                    embryogenesis  growth,   glycemia,
                                         10
                    prolactin levels, blood pressure, heart
                    rate, 11, 12  or body temperature.  CBD
                                              13
                    shows no significant effect on short-term
                    memory or other cognitive aspects. 14
                    The most reported side effects of CBD
                    are tiredness, diarrhea, and changes in
                    appetite.

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