Page 47 - FoodFocusThailand No.163 October 2019
P. 47

STRATEGIC R&D



                     Strengths of Personalized             Personalized nutrition, therefore, is the aspect of food and health that gain a lot of
                     Nutrition                          attention. However, personalized nutrition requires substantiation with scientific evidence
                        •  Interindividual variation in   in these 2 areas. Firstly, the well-designed randomized controlled trials enrolling participants
                     response to dietary factors is a real   based on pre-selected genotypes. This research needs expertise from different disciplines,
                     phenomenon.                        such as, behavioral psychologists, computer scientists, biomedical scientists and
                        •  Some studies have shown that   nutritionists. Secondly, study in terms of “omics” is needed. Omics study will provide
                     personalized nutrition results in greater   greater  mechanistic  information,  for  example,  epigenomics,  metabolomics,  and
                     improvement in diet than traditional   microbiomics.
                     nutritional approach.                 However, not only personalized nutrition may reduce all the risks for diseases and
                        •  Personalized nutrition may foster   support to have good health but also other factors contribute to that. This is due to the
                     sustained change in behavior.      complexity of body.
                        •  The personalized nutrition
                     approach or precision medicine will
                     drive scientific developments beneficial
                     for personalize nutrition and therefore
                     public health.
                     Weaknesses of Personalized
                     Nutrition
                        •  Scientific  evidence  for
                     personalized nutrition is mostly based
                     on observational studies with low
                     reproducibility.
                        •  The theoretical basis for
                     personalized nu tritio n is
                     underdeveloped.
                        •  The persistence over time and
                     heritability of interindividual differences
                     in response to dietary factors are
                     mostly unknown.
                        •  There  are  few  well-designed
                     randomized controlled trials that
                     demonstrate the efficacy and safety of
                     personalized nutrition.
                        •  Most commercial offerings in the
                     personalized nutrition are based on
                     direct to consumer tests that are
                     unregulated and have limited public
                     evidence.


































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