Page 45 - FoodFocusThailand No.182 May 2021
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STRATEGIC R & D


                     •  Maintain normal levels of cholesterol and blood sugar.  to avoid incurring large expenses associated with treatment and care.
                     •  Avoid excessive consumption of alcohol and get a minimum   Support equipment for stabilization, such as cane or handrail, is thus
                       7 hours of sleep.                               essential to this aim. Regular physical activities and maintenance of
                     •  Reduce stress by engaging in stress-alleviating activities such    cardiovascular health may, therefore, temporarily keep cognitive
                       as socialization, yoga, meditation, exercise, and non-smoking.  neurodegeneration at bay.
                     In the United States, 14% of the 71-year-old population and 50%   Additionally, social withdrawal, high stress, long working hours, sleep
                  of the over 85-year-old population suffer from dementia, which   deprivation, shift working, extreme cold, or loud noises give rise to
                  encompasses losses of learning ability and motor skills and inhibits   accumulated physical lassitude and heighten the risks of cardiovascular
                  daily routines. This condition, if caused by cerebral embolism, is called   diseases and stroke, which may, in turn, lead to cognitive neurodegeneration
                  vascular dementia and will lead to progressive cognitive decline.   and eventually dementia.
                  Vascular dementia is the second most common cause of dementia   Participating in social activity helps mitigate the progress of cognitive
                  after Alzheimer’s disease, which is the most common cause.   decline. It is reported that regular social activities and new experience
                  Alzheimer’s disease is caused by intracerebral formation of beta   acquisition can slowdown the functional regression of the brain for up to
                  amyloid plaques and tau tangles, which disrupt the cerebral neural   6 years, and those who keep away from social activities run 60% more
                  network, cause cerebral cellular death, and induce mild cognitive   risks of suffering from cerebral neuronal degeneration because social
                  impairment (MCI) – an early sign of degenerative cognitive loss that   activities help keep many cognitive processes such as memorization,
                  occurs in 1-2% of the population of over 65 years of age and may   thought processing, and visuospatial ability activated.
                  progress into dementia.
                     Fifteen percent of type-2 diabetic patients over 80 years old are  Important Nutrients for Brain Health
                  found to be afflicted with dementia deriving from inflammation, oxidative   Magnesium: Magnesium can also come in the forms of magnesium
                  stress, and arteriosclerosis-inducing condition called endothelial   citrate, magnesium chloride, and magnesium oxide
                  inflammation. The cause of these conditions is insulin resistance, which   Vitamin B:  Vitamins B6, B9, and B12 are essential nutrients in almost
                  induces heightened blood sugar levels. Well-regulated blood sugar   all food supplement formulas for brain health. Vitamins promote the brain’s
                  levels will, therefore, ensure healthier brain in diabetic patients. A strict   signal transmission and the synthesis of new brain cells.
                  control of blood sugar levels has been reported to be more effective   Choline: Choline is particularly vital to adults and pregnant women.
                  than other approaches to delay the progressive loss of learning ability   There is evidence that choline plays an important role in the development
                  and amnesia.                                         of the cerebral region that involves memory, and it also improves long-
                                                                       term memory. Choline deficiency may contribute to higher risks of learning
                  What Is Cognitive Functioning?                       impairment. Choline is also important for long-term memory improvement.
                  Cognitive functioning refers to overall mental abilities that span learning,   Vitamin E: Vitamin E assists in cognitive and learning functions as
                  thinking, reasoning, memory, problem-solving, decision-making,   its antioxidant properties can help eliminate oxidation in the brain.
                  concentration, and attention. These functions are categorized under   GABA:  A  sufficient  amount  of  GABA  is  beneficial  to  memory,
                  general  intelligence  (g),  fluid  intelligence  (Gf),  and  crystallized   concentration, stress alleviation, and sleep quality.
                  intelligence (Gc): general intelligence (g) encompasses general learning   Amino acids: Amino acids such as creatine and leucine promote
                  abilities; fluid intelligence (Gf) involves logics, processing speed — the   cerebral functions as they serve as neurotransmitter precursors. These
                  time it takes to learn, understand, and react to any given data such as   amino acids are used as ingredients in the food supplements designed
                  visual information (sentence and number) and auditory information   for short-term memory improvement.
                  (language) — and problem-solving abilities in unfamiliar circumstances;   Omega-3: Omega-3 fatty acid, EPA, and DHA play an important role
                  crystallized intelligence (Gc) concerns the knowledge and experience   in the development of brain and heart health. Omega-3 is especially
                  accumulated during a lifetime, which can be measured by the size of   beneficial when brain health is affected by air pollution. In an experiment,
                  vocabulary memorized during one’s lifetime. Gf reaches its peak in the   1,315 female participants of average age of 75 years who lived in areas
                  early adult stage, around 20 years of age, and will gradually decrease   with extremely high air pollution regularly ingested fish-derived omega-3:
                  until the later stages of life. Gc, on the other hand, will increase in   it was revealed that none of them showed any sign or symptom that may
                  proportion to age as long as new knowledge and experience are   afterward develop into dementia.
                  continuously acquired. However, there is also evidence that learning   The aging population is gradually expanding. Monitoring and taking
                  and cognitive abilities will, in general, diminish with age.   care of the elderly’s health are essential but can also incur large long-term
                     Neurology researchers reveal that age can negatively affect the   expenses. Maintaining good physical, mental, and brain health in the later
                  reasoning ability and processing speed under the influence of Gf due   stage of life can extend life expectancy and improve life quality, thus
                  to the age-related degeneration of white matter, which is a vital   reducing the elderly population’s needs for assistance. Longevity and
                  substance that oversees effective cerebral neuronal network. Elderly   healthy brain are more pleasant than and take priority over physical
                  individuals are more likely to be afflicted with lower Gf due to the rise   wellness.
                  of anomalies in aging white matter. The skills under the influence of
                  Gc, however, can still retain their stability and even become more
                  refined in proportion to increasing age and experience.    เอีกสารอี้างอีิง/References
                     A hypothetical method to retain learning ability involves engagement   Brain Health: A Mysterious Frontier. Available from:  www.nutraceuticalworld.com
                  or participation in an activity or an environment conducive to mental   Gerald J. and Dorothy R. 2020. Preserving brain health through a heart-healthy diet.
                  stimulation and neuronal development. In addition, lack of physical     Health & Nutrition Letter. Available from: www.nutritionletter.tuft.edu
                                                                       Gwenith G. Fisher. 2019. Theory of Cognitive Aging and Work. Work Across the
                  activities, such as brisk walking or grasping exercise, may contribute     Lifespan. Available from: http://doi.org/10.1016/B978-0-12-812756-8.00002-5
                  to cognitive decline. An elderly with cognitive impairment is more prone   Sonja Spitzer. 2019. Reporting biases in self -assessed physical and cognitive health
                                                                         status of older
                  to injury and accident, such as tripping, as the motor skills that regulate   Europeans. PLOSS ONE. Available from: https://doi.org/10.1371/journal.pone.0223526
                  balanced walking gait depend on cognitive resources such as   Yuri Jang. 2021. Cognitive health risks posed by social isolation and loneliness in
                  concentration and posture stabilization. Slipping or tripping injuries in     older Korean
                                                                       Americans. BMC Geriatrics. Available from: https://doi.org/10.11861/s12877-021-
                  the elderly are attributed to progressive cognitive impairment, and     02066-4
                  these patients tend to suffer from partial amnesia as well. Therefore,   Zachary A. Marcum. 2020. Beliefs about benefits and harms of medications and
                  priority should be given to the prevention of tripping or slipping injuries     supplements for brain health. Preventive Medicine Reports. 17(22020)101060.
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